O SHARAPOV1,2, S ABDULLAEV2
1Republican Specialized Scientific Practical Medical Center Of Nephrology And Kidney Transplantation, Tashkent, Uzbekistan, 2Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan
Aim: Study left ventricular myocardial remodeling in patients with diabetic nephropathy and arterial hypertension.
Background: The development of diabetic nephropathy significantly worsens the prognosis in patients with diabetes mellitus, therefore, timely diagnosis and treatment of this pathology is extremely important.
Methods: 37 patients with CKD stage 3 diabetic etiology and arterial hypertension were examined. The average age of patients was 47.6±5 years. The initial mean systolic blood pressure (SBP) was 159.3±12.5 mmHg, the average diastolic blood pressure (DBP) was 95.1±7.3 mmHg. eGFR was 38.4 ± 11.3 ml/min/1.73 m2.
Results: Concentric hypertrophy, eccentric hypertrophy, and concentric LV remodeling were found. 25 patients had LV concentric hypertrophy, 7 patients had LV concentric remodeling, 5 patients had LV eccentric hypertrophy. The indicators of the thickness of the MFP averaged 13.1±1.22 mm, the thickness of the WLW – 12.5±1.64 mm, MMLV – 243.3±36.6 g, IMMLV – 152.3±29,1 g/m2, respectively.
Conclusions: As the results of our study showed, all patients with diabetic nephropathy and hypertension had LV hypertrophy, while the vast majority of patients (25) were diagnosed with a concentric type of LV myocardial hypertrophy.
Young nephrologist from Uzbekistan