E ERNA FITRISIA CHRISTINA 1, I KUSWADI 1, W YULIA 1
1Indonesian Association Of Internal Medicine, Klaten, Indonesia
Aim: To observe outcomes and the differences of the association between stages of acute kidney injury (AKI) and variables in the characteristic patients (body mass index (BMI), comorbid conditions, laboratory values, and vital signs).
Background: AKI is an important complication in COVID-19. The reported incidences vary widely all over the world. Data of AKI in COVID-19 patients in Indonesia remains insufficient.
Methods: This study used retrospective, observational data reviewed from the health records of patients aged more than 18 years hospitalized in Sardjito General Hospital from March 2020 to January 2021 with laboratory-confirmed COVID-19 and the incidence of AKI.
Results: Of 467 hospitalized patients confirmed COVID-19, AKI occurred in 47 (10,06%) patients, analysed by Kruskal Wallis and Chi-Square test. 38 (80,85%) patients were male, 9 (19,14%) patients were female. The proportions with stage 1, 2, or 3 AKI were 32 (68,08%), 7 (14,89%), 8 (17,02%) patients respectively. Of the 27 (57%) patients were admitted to intensive care, 18 (66,66%) patients required mechanical ventilation. 7 (14,89%) patients required renal replacement therapy with hemodialysis or continuous vena venous hemofiltration. In hospital mortality was 27 (57%) patients. Stage AKI was significantly associated with BMI and diabetes mellitus (DM). In BMI and DM, stage 1 has highest AKI levels (p=0.032, mean rank stage 1=26.25, stage 2=13.07, stage 3=24.56 and p=0.036, mean rank stage 1=26.78, stage 2=19.86, stage 3=16.50, respectively). Regarding neither laboratory values nor vital signs had a significant association with stage AKI.
Conclusions: AKI in COVID-19 is associated with high mortality. Stage AKI is associated with a significant risk for death, there are BMI and comorbid DM.
Keywords : COVID-19, AKI, body mass index, diabetes mellitus
My name is Erna Fitrisia Christina, date of birth November, 26th, 1977, gender female, address Cokrokembang RT 6 RW 19 Tulung Klaten Central Java Indonesia, married, Indonesian. Cellphone +6282225582714. Email : firstname.lastname@example.org. Graduated from medical faculty of Sebelas Maret University at 2004. Graduated internal medicine from Gadjah Mada University at 2011. Now, I am trainee of Nephrology and Hypertension sub specialization study program Internal Medicine, Faculty of Medicine-Public Health and Nursing Gadjah Mada University, Indonesia