Royal Children’s Hospital, Melbourne
David Metz works at the Royal Children’s Hospital, Melbourne as a paediatric nephrologist, clinical pharmacologist, and physician on the apheresis service.
He has recently submitted his PhD thesis through the University of Melbourne (2020), examining strategies to improve kidney transplant outcomes through individualised immunosuppressant dosing. This included a multi-site prospective pharmacokinetic trial, time-to-event analysis of registry data and population pharmacokinetic modelling.
He has advocated for individualised dosing of mycophenolic acid based on critical re-appraisal of the evidence and using target concentration principles, as discussed in publications in Transplantation (PMID: 31584924) and the British Journal of Clinical Pharmacology (PMID: 32543717).