Q CAO1, H YI1, A J. GILL2, M FOLEY3,4, C HUANG1, X CHEN1, C A. POLLOCK1 1Kolling Institute of Medical Research,Royal North Shore Hospital, Sydney Medical School, University of Sydney, St Leonards, Sydney, Australia, 2Department of Anatomical Pathology, NSW Health...
- 20 October 2020
E SMITH1,2, T HEWITSON1,2 1Royal Melbourne Hospital, Melbourne, Australia, 2University of Melbourne, Melbourne, Australia Aim: To define the mechanisms of metabolic reprogramming that occur in fibroblast activation Background: TGF-β1 reprograms metabolism in renal fibroblasts, inducing a switch from oxidative phosphorylation...
- 20 October 2020
F YANG1,2, E OZOLS1, K LEONG1, F MA1, X JIANG2, D NIKOLIC-PATERSON1 1Monash Health, Clayton, Australia, 2Department of Pediatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou , China Aim: To investigate the role of the c-Jun amino terminal...
- 19 October 2020
M YEN LEE1,2, P TEMPLE-SMITH2, D NIKOLIC-PATERSON1 1Department of Nephrology, Monash Health and Monash University Centre for Inflammatory Diseases, Clayton, Australia, 2Department of Obstetrics and Gynaecology, Monash Health and Monash University, Clayton, Australia Aim: To investigate whether recombinant follistatin can...
- 19 October 2020
G H TESCH1,2, F Y MA1,2, S S BADAL3, J T LILES3, D J NIKOLIC-PATERSON1,2 1Nephrology Department, Monash Health, Clayton, Australia, 2Department of Medicine, Monash University, Clayton, Australia, 3Gilead Sciences, Foster City, USA Aim: To assess whether ASK1 blockade inhibits...
- 13 October 2020
C HUANG1, H YI1, Y SHI1, Q CAO1, X-M CHEN1, C POLLOCK1 1Kolling Institute, University Of Sydney, Sydney, Australia Aim: To identify the role of KCa3.1 in mitophagy in diabetic kidney disease. Background: Mitophagy, the selective degradation of mitochondria by...
- 12 October 2020